Release of enkephalins and enkephalin-containing polypeptides from perfused beef adrenal glands.
نویسندگان
چکیده
Enkephalins and enkephalin-containing polypeptides were released from perfused bovine adrenal glands by nicotine and Ba2+, agents that release catecholamines. All the enkephalin-containing polypeptides that are normally found in the adrenal medulla were released by the two secretagogues in approximately the same proportions as are present in adrenal chromaffin granules.
منابع مشابه
Marked increases in large enkephalin-containing polypeptides in the rat adrenal gland following denervation.
When rat adrenal glands are denervated, large increases in the amounts of enkephalin and enkephalin-containing polypeptides appear. In the normal gland, only trace amounts occur. One of the larger polypeptides (approximately 22,000 daltons) increases rapidly and by 48 hr following denervation, attains 20 times its original level. At this time, the levels of free enkephalins are essentially unch...
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ورودعنوان ژورنال:
- Proceedings of the National Academy of Sciences of the United States of America
دوره 77 12 شماره
صفحات -
تاریخ انتشار 1980